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Erin Lavik and Tarek Fahmy win biomedical engineering awards Two Yale scientists have won Wallace H. Coulter Foundation Early Career Translational Research Awards in Biomedical Engineering. The winners, Erin Lavik and Tarek Fahmy, are both assistant professors in biomedical engineering. The Wallace H. Coulter Foundation is a private, non-profit foundation dedicated to improving human health care by supporting translational research in biomedical engineering. The awards are intended to encourage and assist investigators as they establish themselves in academic research careers that involve translational research. Those receiving an award must have a primary appointment in a biomedical engineering department, be collaborating with an investigator in a practicing clinical environment and have received a doctoral degree within the previous six years. Lavik received the award for her project "Sustained delivery of timolol maleate for management of elevated IOP for glaucoma," in collaboration with Young Kwon and Markus Kheun at the University of Iowa. "There are medications that lower intraocular pressure (IOP) very successfully, but need to be administered several times a day," explains Lavik. "Unfortunately, many patients with glaucoma are not able to administer eye drops several times a day effectively, and they suffer increased IOP, nerve damage, and ultimately may lose their sight. By developing a long-term delivery system, we seek to ease this problem and lay the foundation for the delivery of other drugs in the eye." Fahmy received the award for his project "Multimodal nanoparticles for targeting autoimmune T cells in systemic lupus erythematosus: A strategy for non-invasive diagnosis and targeted drug delivery," a collaboration with Joseph Craft in the Department of Immunobiology at Yale. "We have developed a platform technology that promises to simultaneously detect cells that cause autoimmune disease by magnetic resonance imaging, and deliver drugs to those cells," says Fahmy. "The approach is driven by an expert understanding of the basic and clinical science coupled to a promising novel nanotechnology that is rapidly translatable to the clinical setting." W. Mark Saltzman, professor and chair of Yale's Department of Biomedical Engineering, says, "These Early Career Awards acknowledge excellent science, and are specifically targeted to innovative biomedical engineering research that will impact clinical care. Excellence in translational medicine is the focus of our new department." The awards are for two years of research funding, and winners will be honored at an event in conjunction with the annual meeting of the Biomedical Engineering Society in October. The awards program honors the belief of the foundation's benefactor, Wallace H. Coulter, that the results of research must be taken to the stage of a commercially viable product in order to truly benefit humanity. Coulter's discovery of an electronic method of counting and classifying microscopic particles suspended in fluid led to the development of an apparatus to count and classify blood cells, a procedure previously done manually. The "Coulter Counter" revolutionized the practice of clinical laboratory medicine.
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