The Yale BioHaven Entrepreneurship Seminars series’ first program in
2008 will focus on the New Haven start-up company Rib-X Pharmaceuticals Inc.
The program will be presented on Tuesday, Feb. 12, 4-5 p.m. in the Anlyan Center
Auditorium, Yale School of Medicine, 300 Cedar St.
The featured speakers from Rib-X will be Susan Froshauer, president and chief
executive officer, and Erin Duffy, vice president of structure-based drug design.
They will discuss the Rib-X research goals for design of proprietary classes
of antibacterial agents.
Rib-X focuses on the design and development of novel small-molecule antibiotics
for the treatment of antibiotic-resistant infections in hospital and community
settings. Since its inception in 2001, Rib-X has established a portfolio of
development and discovery-stage antibiotic compounds, including RX-3341,
a broad-spectrum intravenous quinolone antibiotic that will soon
enter Phase 3 studies, and RX-1741, an orally administered oxazolidinone antibiotic
now in two Phase 2 studies.
Many classic antibiotics work by inhibiting operation of the ribosome — a
part of the protein synthesizing machinery that is essential for the function
of all bacterial pathogens. A key advantage for Rib-X is proprietary access
to the high-resolution crystal structure of the ribosome, which provides physical
and chemical information for designing useful small molecules.
Rib-X raised $50 million in a Series C Preferred Stock financing announced
in June of 2006, bringing the total amount raised by the company to $123 million.
Refreshments and an opportunity to network will follow the seminar 5-7 p.m.
Registration is free, but advanced registration is required. To RSVP, send
an e-mail to biohaven@yale.edu or call the Yale Office of Cooperative Research
at (203) 436-8096. A flyer about all events in the series is online at http://curenet.org/download/biohaven.pdf.
Directions to the event are available online at http://info.med.yale.edu/maps/cab.html.
Yale BioHaven Entrepreneurship Seminars are sponsored by the Yale Office of
Cooperative Research, Connecticut United for Research Excellence (CURE), Wiggin
and Dana LLP, Elm Street Ventures, and Price Waterhouse Coopers PC, with support
from Yale Entrepreneurial Society and Yale Biotechnology & Pharmaceutical
Society. For further information on the seminar, contact Tracy Huang at (203)
436-8096 or tracy.huang@yale.edu.
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