In its Dec. 20 issue, The Lancet cited a paper co-authored by Kenneth K. Kidd, professor of genetics and psychiatry, as the most important biomedical research paper of the past year published in any source.
Many notable awards, including the Nobels and Lasker, recognize the achievements of individuals rather than the notable work of teams. Lancet Editor Richard Horton commented, "With this prize, we aim to salute truly first-class advances in thinking or practice which would otherwise go unnoticed by the contemporary establishment of science."
The winning paper was titled "Genetic Structure of Human Populations," which appeared in the journal Science on Dec. 20, 2002.
The paper was nominated by a member of Lancet's International Advisory Board, who noted that the paper has two very important messages: one general biological and one methodological. The biological message is that the overwhelming source of human genetic variation is between individuals and not between ethnic groups, said the nominator, while the methodological is that for assessing genetic risk, investigators can use standard study designs, as long as self-reported ethnic background is taken into account.
Kidd noted that "most people have a certain amount of fascination with their own origins, not just their genealogy, but the culture, history and geography of where they came from. This work statistically evaluates those similarities and differences."
In addition to Kidd, the authors of the international collaborative study included Noah Rosenberg, University of Southern California; Jonathan K. Pritchard, University of Chicago; James L. Weber, Marshfield Medical Research Center, Wisconsin; Howard M. Cann, Center for the Study of Human Polymorphisms, Paris; Lev A. Zhivotovsky, the Russian Academy of Sciences, Moscow; and Marcus W. Feldman, Stanford University.
-- By Janet Rettig Emanuel
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