Andrew D. Hamilton, the newly named Benjamin Silliman Professor of Chemistry, is a noted researcher in bio-organic chemistry -- particularly focusing on molecular recognition and molecular interactions -- who also serves as the University's deputy provost for science and technology.
In his scientific research, Hamilton has explored the synthesis of small molecules that can interact with biological molecules and influence biological processes. His studies have offered new insights into drub design and the development of possible therapies for cancer.
Hamilton also worked with a team that developed high-potency compounds that have been licensed to the non-profit pharmaceutical company OneWorld Health for testing as potential drugs to treat Chagas disease, a parasitic disease that is the leading cause of heart failure in Latin America. He also worked on a team at Yale that succeeded for the first time in turning supercritical carbon dioxide into gel form, resulting in a more environmentally friendly solvent for oil recovery and other uses.
For his work on molecular recognition, artificial enzymes and enzyme inhibition, Hamilton was recently elected as one of 44 new fellows of the Royal Society, whose members include the most distinguished scientists from the United Kingdom, other Commonwealth countries and the Republic of Ireland. Current members include 68 Nobel Prize winners; former members include Isaac Newton and Charles Darwin.
Hamilton taught at the University of Pittsburgh from 1988 to 1997, when he joined the Yale faculty as the Irénée duPont Professor of Chemistry. He has chaired the Department of Chemistry since 1999. Since 1998, he has held a joint appointment in the Department of Molecular Biophysics and Biochemistry. He was named deputy provost in 2003.
The Yale scientist earned his undergraduate degree from Exeter University, a master's degree from the University of British Columbia and his Ph.D. from Cambridge University. He was a postdoctoral fellow at the Université Louis Pasteur in Strasbourg and later taught at Princeton University from 1981 to 1988.
Hamilton has been invited to give named lectures at numerous universities. His other honors include an Arthur C. Cope Scholar Award from the American Chemical Society.
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