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May 19, 2006|Volume 34, Number 29|Three-Week Issue


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Treatment preferences for end-of-life care may change with time and declining health

Over time, older people change their preferences for end-of-life care and are more willing to accept treatment resulting in physical disability than treatment resulting in cognitive disability, researchers at the School of Medicine report in the current Archives of Internal Medicine.

Advance care planning, the process by which patients indicate the medical care they would want to receive if they could no longer make decisions for themselves, asks patients to indicate whether they would want various life-sustaining treatments.

"This process asks patients to predict what their future preferences would be, and therefore assumes that preferences will not change over time," says first author Dr. Terri Fried, associate professor of internal medicine, geriatrics. "This study demonstrated that patients' preferences changed over time and with changes in their health state, raising questions about patients' abilities to predict their future preferences."

Trained research assistants conducted in-home interviews with 226 persons who were age 60 and older and seriously ill with cancer, congestive heart failure or chronic obstructive pulmonary disease. Interviews were conducted at least every four months for up to two years and more frequently with changes in the patient's health status.

Patients facing a worsening of illness were asked to rate whether treatment for their illness would be acceptable if it resulted in a series of health states. A rating of "unacceptable" meant they would prefer to die than to receive treatment.

Over time, patients became more likely to rate as acceptable treatment resulting in mild or severe physical disability. Patients who experienced a decline in their ability to perform complex activities of daily living were more likely to rate treatment resulting in mild or severe disability as acceptable. These patients became less likely over time to rate as acceptable treatment that would result in severe cognitive disability.

Other authors on the study were Amy L. Byers, William T. Gallo, Peter H. Van Ness, Virginia R. Towle, John R. O'Leary and Joel A. Dubin.

-- By Karen Peart


T H I SW E E K ' SS T O R I E S

Scientists identify new genus of monkey; first in 83 years

Divinity Dean reappointed to second term

Yale to celebrate 305th Commencement

Student photographs 'hidden beauty in everyday life'

Summertime at Yale

Brownell cited as one of world's '100 most influential people'

President Levin honored for increasing town-gown partnerships

ENDOWED PROFESSORSHIPS

Four individuals will bring their expertise . . . to SOM

Two noted violinists . . . join the faculty of the School of Music

Three residential college masters named to second term
Laura Cruickshank named to post of University planner

Exhibit features English silver pieces once owned by tsars

Exhibits look back at 40 years of chiming bells and more

Major renovation effort begins at Cross Campus Librar

MEDICAL SCHOOL NEWS

Eight graduating seniors are bound for China as teaching fellows

IN MEMORIAM

Yale's nurse-midwives celebrate 50 years of community care

Talk will focus on life extension and human right

'Keepers of the Dream' to look at advancing urban education

Sociologist Adams honored for book on 'The Familial State'

Association honors Yale-affiliated scientists and engineers . . .

Journal of Industrial Ecology marks two milestones . . .

Grant will fund research on how human speech is shaped

'Trouble in Tahiti' to be performed during School of Music alumni weekend

Campaign invites community to 'Plant a Row for the Hungry'

Campus Notes


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