 | Dr. Jack Elias |
A Yale scientist will discuss his pioneering work on asthma and lung disease and five Yale School of Medicine students will describe their prize-winning studies during Student Research Day on Tuesday, May 8, in the Jane Ellen Hope Building, 315 Cedar St.
The annual program showcases the original research completed by every graduating Yale medical school student. The Yale School of Medicine is the only one in the country with a long tradition of requiring that candidates for an M.D. degree write a dissertation based on original research, notes Dr. John N. Forrest Jr., professor of internal medicine and director of the Office of Student Research.
The day will begin with a scientific poster session noon-2 p.m. in the corridors of the Hope Building. This event and the day's talks are free and open to the public.
At 2 p.m., five students who won prizes for their projects will discuss their research in Rm. 110. Four are working toward their M.D. degrees. Their names, the department in which they have done research and their project titles are: Brent Schultz, surgery, "Epi-genetic abnormalities of infantile hemangiomas: Regulation of the IGF2/H19 locus"; Rajesh Rao, laboratory medicine, "Platelet-derived growth factor enables direct derivation of oligodendrocyte progenitors from CNS stem cells"; Bernice Ng, dermatology, "Chronic inflammation-driven tumor promotion associated with CD8+ T cells"; Paul Kalanithi, Yale Child Study Center, "Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette Syndrome." In addition, Ranjit S. Bindra, who is seeking an M.D./Ph.D. in therapeutic radiology and experimental pathology, will discuss his project, "Regulation of DNA repair in hypoxic cancer cells."
At 4 p.m., Dr. Jack Elias, the Waldemar Von Zedtwitz Professor of Medicine and chair of the Department of Internal Medicine and chief of the Section of Pulmonary and Critical Care Medicine at Yale, will present the 20th annual Farr Lecture in Rm. 110.
Elias' research is focused on the cellular and molecular biology of the lung, and processes related to both injury and repair. He has studied asthma, emphysema, pulmonary fibrosis and acute lung injury. His research group has developed and studied genetic models of these diseases and translated findings in these models to human disorders. This work has validated therapeutic targets for pharmaceutical companies seeking to develop new therapies for these conditions.
Elias, who has trained more than 50 investigators now working in academia and industry, has seven patents or pending patents based on his research. He has been a member of the Association of American Physicians since 1998 and a councilor since 2003. He has held more than a dozen posts for the American Thoracic Society/American Lung Association, including chair of its long-range planning and scientific advisory committees and of the Scientific Assembly on Allergy, Immunology and Inflammation. He is also a participant in strategic planning for the National Heart, Lung and Blood Institute.
He is the author of more than 160 original journal articles and 200 abstracts and is co-editor of the textbook "Fishman's Pulmonary Diseases and Disorders." He is principal investigator of four current R01 awards, a T32 training grant, and a P01 program project grant from the National Institutes of Health.
T H I S
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