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Karyn Frick honored for contributions to women’s health
Karyn Frick, associate professor of behavioral neuroscience in the Department
of Psychology, has been awarded the third annual Society for Women’s
Health Research Medtronic Prize for Scientific Contributions to Women’s
Health for her research on the effect of hormones on learning and memory.
Frick received $75,000 from the society at its annual awards banquet on April
28.
Frick’s lab is studying how the hormones estrogen and progesterone influence
the brain’s ability to learn and remember. Scientists know that, both
before and after birth, these hormones help to keep cells in women’s
brains healthy, and that after puberty, hormone fluctuations during the menstrual
cycle influence how women think, feel and remember. Researchers believe that
at menopause, the loss of hormones significantly increases a woman’s
risk of memory loss and Alzheimer’s Disease.
Frick has demonstrated that hormone loss in middle age causes premature memory
decline in female mice relative to males. She has also studied whether hormone
treatment in middle-aged and older female mice can improve memory. She has
discovered a molecule in the brain that is necessary for estrogen to improve
memory, and her lab is studying whether this molecule also works with estrogen
to reduce memory loss in aging females. Ultimately, scientists such as Frick
hope to develop drugs that prevent memory loss in menopausal women but do not
produce the negative side effects of current hormone therapies.
Frick, who also holds appointments in the Interdepartmental Neuroscience Program
and the Biological and Biomedical Sciences Program, has been a professor in
the psychology department at Yale since 2000.
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