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His research has focused on how trends in cancer epidemiology are described, especially through the use of age-period-cohort models. He also collaborated with the National Acute Spinal Cord Injury Study to help develop new ways of analyzing data collected from clinical trials of patients with this injury. The author of the recent book "Multivariate Methods in Epidemiology," Holford has also written more than 160 scientific articles and papers on such topics as breast and other cancers, environmental health and perinatal epidemiology. He has been the founding editor since 1990 of "Statistical Methods in Medical Research."
Holford holds a joint appointment in the Department of Epidemiology and Public Health (EPH) at the School of Medicine and the Department of Statistics.
A graduate of Andrews University in Michigan, Holford earned his Ph.D. in 1973 at Yale, where he focused on biometry. He joined the Yale faculty in 1974 as an assistant professor of public health and was promoted to a full professorship in 1989. He has held a number of administrative posts during his tenure, most recently serving, from 1997 to 2002, as director of graduate studies in EPH, and, from 1999 to 2002, as associate director of the medical school's Investigative Medicine Program. He was acting dean for public health and acting chair of EPH from July through December 2001. In addition, he served in the mid-1980s as acting head of the Division of Biostatistics in EPH.
The current associate editor of the Journal of Epidemiology and Biostatistics, Holford has also served in that role on the American Journal of Epidemiology and Biometrics.
Holford has received a number of honors for his work, including an Eleanor Roosevelt International Cancer Fellowship from the International Union Against Cancer and the Wakeman Award for Research in the Neurosciences. He is a fellow of the American College of Epidemiology and is a member of the American Association for the Advancement of Science, the American Statistical Association, the Biometric Society and the Society for Epidemiological Research.
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