Nancy H. Ruddle X

Nancy H. Ruddle, the newly appointed John Rodman Paul Professor of Epidemiology and Public Health, is a noted immunologist whose study of the function and structure of cells and cytokines has contributed to an understanding of such autoimmune diseases as diabetes, multiple sclerosis and AIDS, as well as cancer.

Ruddle is known for her discovery and analysis of lymphotoxin, a protein produced by T cells that plays a role in the protective immune system and destroys tumor cells. She and researchers in her laboratory have engaged in research on the lymphotoxin/
tumor necrosis factor family, their regulation and roles in lymphoid organ development and pathogenesis of viral and autoimmune disease. The more than 130 scientific articles Ruddle has authored or co-authored have explored the immunology of such diseases as leukemia, allergic encephalomyelitis and Leishmania amazonensis infection, among others.

Ruddle is director of graduate studies in the School of Medicine's Department of Epidemiology and Public Health (EPH) and is a professor in the Section of Immunobiology. She headed the EPH microbiology department from 1990 to 2001. She was the acting chair and associate dean for Public Health 1993-1994 and was acting chair and acting dean of Public Health in 2002.

A graduate of Mount Holyoke College, Ruddle earned her Ph.D. in microbiology at Yale in 1968 and continued work at the University as a research associate in the surgery department and lecturer in the microbiology department. From 1971 to 1974 she was a postdoctoral fellow and lecturer. She joined the faculty as an assistant professor in EPH in 1975, was promoted to a tenured associate professorship in 1985 and became a full professor in 1991. She also serves as a member of the Yale Cancer Center.

Ruddle has served on advisory panels and ,study sections of the National Science Foundation, the National Institutes of Health and the Multiple Sclerosis Society, Inc., among others. She currently is on the editorial boards of Cytokine and of Immunology Letters.

The recipient of the Juvenile Diabetes Foundation's International Mary Jane Kugel Award in 1995, Ruddle has also been honored for her research on four occasions by the Greater New Haven Chapter of the National Multiple Sclerosis Society. She is a member of the American Association of Science and the American Association of Immunologists and president of the International Cytokine Society.

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ENDOWED PROFESSORSHIPS

• Holford appointed as Bliss Professor in EPH
  
  
• Morse named to Dudley chair in engineering
  
  
• Ruddle designated as Paul Professor in EPH
  

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MEMORIAL SERVICES

• Dr. Gustaf Lindskog
  
  
• Dr. Albert J. Solnit
  
  
• Andrew Forge
  

Campus Notes

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