David McCormick, professor of neurobiology at the School of Medicine, has received the Senator Jacob Javits Award in the Neurosciences for his proposal to study the basic operational mechanisms of the cerebral cortex.

The Javits Award is made by Congress in honor of the late U.S. senator from New York with advice from the National Advisory Neurological Disorders and Stroke Council. Investigators who are eligible for Javits Awards have submitted regular research grant applications for competitive review, have a distinguished record of substantial contributions in a field of neurological science and are expected to be highly productive over the next seven years.

McCormick was selected for his research titled "Neurotransmitter Actions in Neocortex and Thalamus." His studies address the delicate balance between excitation and inhibition that is precisely maintained and that allows the cortex to perform normal functions including the generation of persistent activity associated with working memory and attention.

McCormick is studying the cellular mechanisms of the basal operations of the cerebral cortex and how it rapidly controls its own excitability, allowing it to perform behavioral tasks without causing epileptic seizures.

The researcher's work is expected to contribute to basic knowledge about the nature of cortical activity and increase understanding of seizures and epilepsy.

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